Juvenile-hormone esterase
| juvenile-hormone esterase | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| EC number | 3.1.1.59 | ||||||
| CAS number | 50812-15-2 | ||||||
| Databases | |||||||
| IntEnz | IntEnz view | ||||||
| BRENDA | BRENDA entry | ||||||
| ExPASy | NiceZyme view | ||||||
| KEGG | KEGG entry | ||||||
| MetaCyc | metabolic pathway | ||||||
| PRIAM | profile | ||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||
| Gene Ontology | AmiGO / EGO | ||||||
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In enzymology, a juvenile-hormone esterase (EC 3.1.1.59) is an enzyme that catalyzes the chemical reaction
- methyl (2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate + H2O
(2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate + methanol
The 3 substrates of this enzyme are methyl, (2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate, and H2O, whereas its two products are (2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate and methanol.
This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name of this enzyme class is methyl-(2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-die noate acylhydrolase. Other names in common use include JH-esterase, juvenile hormone analog esterase, and juvenile hormone carboxyesterase.
References
- Foucher AL, McIntosh A, Douce G, Wastling J, Tait A, Turner CM (2006). "A proteomic analysis of arsenical drug resistance in Trypanosoma brucei". Proteomics. 6 (9): 2726–32. doi:10.1002/pmic.200500419. PMID 16526094.
- Mitsui T, Riddiford LM and Bellamy G (1979). "Metabolism of juvenile hormone by the epidermis of the tobacco hornworm (Manduca sexta)". Insect Biochem. 9 (6): 637–643. doi:10.1016/0020-1790(79)90103-3.